Atlas of Pediatric Peripheral Blood Smears Ebook PDF download
Atlas of Pediatric Peripheral Blood Smears Ebook PDF download Erythrocyte(Red Cell) A normal erythrocyte is a mature non-nucleated red cell appearing as a biconcave disc. It should stain pink to red with a central pallor occupying 1/3 the diameter of the cell with a Wright-Giemsa stain. Normal Morphology (Newborn) When reviewing the peripheral smear of the newborn, one’s perception of “normal” changes dramatically. A normal newborn smear may have a few burr (echinocytes) cells, an occasional nucleated red blood cell, a few targets (codocytes), a few fragmented RBCs (schistocytes), some spherocytes, and some polychromasia, etc.
The important concept is that there is a much wider variation in the type of red cells observed on the peripheral smear of an infant than is seen in the typical adult smear. If these observations were made on an adult blood film, there would be cause for concern; however, on the newborn smear, these findings are considered normal. Another finding that should be noted is that the typical newborn has a high MCV (mean corpuscular volume), so the red cells are macrocytic. Frequently the hemoglobin is elevated, so the red cells and white cells may appear smudgy and distorted. Making a good peripheral smear is the critical first step in the evaluation of the blood smear.