CLINCAL SUBJECTSSPECIALTY-MS/MD/FRCS

Diseases of the Liver and Biliary System in Children Fourth Edition 2018 eBook

Diseases of the Liver and Biliary System in Children Fourth Edition 2018 eBook

Diseases of the Liver and Biliary System in Children Fourth Edition 2018 eBook

 

Diseases of the Liver and Biliary System in Children Fourth Edition 2018 eBook The diagnosis and management of pediatric liver disease has  been transformed since the first edition of this book in 1999. The rapid developments in cellular and molecular genetic techniques have identified new genes, discovered the causes of rare diseases, taught us much about pathophysiology, and  revealed new targets for therapy.

National and international networks utilizing clinical biobanks and databases have helped us consolidate our knowledge and treatment of cholestaticliver disease, biliary  atresia, and acute liver failure.The medical management of pediatric liver disease owes much to the development of new drugs, particularly antiviral therapy, which has changed the outcome for many children and significantly improved the quality of their lives.The successful development of transplantation, now extended to multiorgan transplantation, has dramatically improved the outcome of infants and children with liver or metabolic disease so that many have become adults, completed their education, and contribute equally to society.  This means that it is important for adult hepatologists not only to become familiar with pediatric diseases new to them, but also to learn how best to manage young people with a lifetime of chronic illness.

The investigation and management of most pediatric liver  disease should be based in specialist or transplant units so  that patients benefit from centralized expertise. Nevertheless,  it is essential for general pediatricians to recognize the early presentation of liver disease, know when to refer to a specialized unit, and be aware of the range of new therapies and their complications, especially transplantation.

The fourth edition of this book summarizes the advances  of the last few years, and provides a practical approach to the
diagnosis and management of pediatric liver diseases, highlighting the importance of multidisciplinary team working  and holistic management of the child and family.

The remit has been extended to include information on  structure and function, immunology, and genetics with an  emphasis on basic mechanisms of disease.

New chapters  describe the effects of liver and kidney disease, combined  liver and kidney transplantation, the management of  anesthesia and intensive care for children with liver disease, and a summary of what the adult hepatologist needs  to know. The book should interest the adult gastroenterologist and  hepatologist, the general pediatrician, and pediatric trainee
as well as provide guidance to nurses and allied health  professionals.

Diseases of the Liver and Biliary System in Children Fourth Edition 2018 eBook

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